Unifying Physics and Biology – Assembly Theory

An international team of researchers has developed a groundbreaking theoretical framework known as assembly theory, uniting the principles of physics and biology to shed light on the evolution and complexity in nature. Published in the esteemed journal Nature, this new work marks a significant advance in our understanding of biological evolution and its interaction with the universe’s physical laws.

The genesis of assembly theory lies in its potential application in life detection, with profound implications for searching alien life and evolving new life forms in the laboratory. The theory revolves around the molecular assembly index, a complexity score assigned to molecules, which is experimentally measurable and correlates with life-derived molecules. This innovative approach bridges the gap between physics and biology, offering a fresh perspective on evolution and the construction of complex objects through natural selection.

Assembly Theory

The recent study introduces a mathematical formalism around a physical quantity called “assembly,” quantifying the selection required to produce complex objects. This concept allows for a deeper understanding of the processes underlying biological complexity and evolution.

Lead author Sara Walker, a theoretical physicist and professor at Arizona State University, emphasizes that assembly theory offers a new lens for viewing physics, chemistry, and biology. It aims to unify inert and living matter, narrowing the gap between reductionist physics and Darwinian evolution.

Furthermore, the theory’s applications are vast, ranging from simple molecules to complex cellular structures, elucidating both the discovery of new objects and the selection of existing ones. It promises open-ended increases in complexity, akin to those observed in life and technology.

Professor Lee Cronin, a co-lead author, highlights that assembly theory redefines our understanding of matter, considering the memory needed to build objects over time. This perspective could revolutionize multiple fields, from cosmology to computer science, standing at the crossroads of physics, chemistry, biology, and information theory.

The researchers aim to refine assembly theory further and explore its applications in characterizing life forms and testing hypotheses about life’s emergence from nonliving matter. The theory’s experimental testability opens up new possibilities for designing experiments to solve the origin of life conundrum.

In conclusion, assembly theory not only provides profound insights into biological complexity and evolutionary innovation but also opens up numerous research directions at the boundary of physical and life sciences.

Sources:

Life from Non-life – Abiogenesis

The search for the origin of life is nothing new. Abiogenesis – life from non life – has fascinated and frustrated science for countless years. But what if we’ve been going about it the wrong way? PROFESSOR LEE CRONIN holds the Regius chair of chemistry at the University of Glasgow. His primary interests are in the creation of artificial lifeforms using inorganic chemistry.

Short Summary for Life from Non Life – How Evolution Powers Everything ~ Professor LEE CRONIN by Merlin

Life from Non-Life: Evolutionary Mechanisms Explained by Professor Lee Cronin

00:23 Professor Lee Cronin’s main interest is in the origin of life and how biology emerged from non-living matter.

02:37 Understanding the mechanism for selection and evolution in the universe.

06:56 Spontaneous generation does not occur without evolution.

09:06 Life is defined by its ability to generate complexity via evolution.

13:00 Evolution and creationism are inextricably linked.

15:14 Creationists lack productive discussion due to their refusal to debate falsifiable hypotheses and faith.

18:44 The UK has vaccinated almost 17 million people, leading to a drop in the death rate.

20:23 Evolution in inorganic world to cells

23:45 Understanding the mysteries of life and the universe through scientific progress

25:35 The theory of signature of life can help determine if something has interacted with a living system or not.

29:11 Evolution can be detected through unique characteristics and can be measured in the lab.

30:49 Experiments per day are out of reach of manual labor, so a new theory for life was built to produce complexity.

34:08 Evolution created biology and biology has sped up the process of evolution.

36:00 The emergence of life on Earth may be as common as the birth of a star in the universe.


Detailed Summary for Life from Non Life – How Evolution Powers Everything ~ Professor LEE CRONIN by Merlin

Life from Non-Life: Evolutionary Mechanisms Explained by Professor Lee Cronin

00:23 Professor Lee Cronin’s main interest is in the origin of life and how biology emerged from non-living matter.

  • Even during the lockdown, the group is continuing their work with additional precautions.
  • Professor Lee Cronin is fascinated by how things work in the universe and believes the process that gave rise to the origin of life is ongoing.

02:37 Understanding the mechanism for selection and evolution in the universe.

  • The curiosity to understand how the universe works, starting with the origins of life.
  • A brief overview of experiments conducted on abiogenesis throughout history.

06:56 Spontaneous generation does not occur without evolution.

  • Spontaneous generation in the past was a result of biological materials already present before sterilization.
  • Defining life is difficult as it is hard to remake or understand something that cannot be defined.

09:06 Life is defined by its ability to generate complexity via evolution.

  • The definition of life has been confused by different interpretations and add-on definitions.
  • Functional information and the ability to generate complexity through evolution are prerequisites for determining if something is alive.

13:00 Evolution and creationism are inextricably linked.

  • Creationists often try to disprove evolution through complexity, but this approach lacks logical discussion and willingness to revise beliefs in light of evidence.
  • Science is about explaining the unknown, and abiogenesis is an area where we are still uncovering the mechanism.

15:14 Creationists lack productive discussion due to their refusal to debate falsifiable hypotheses and faith.

  • Science experiments can be falsified, while faith cannot.
  • Creationists adopt an adversarial front and rely on straw man arguments.

18:44 The UK has vaccinated almost 17 million people, leading to a drop in the death rate.

  • The UK has vaccinated almost 17 million people, which should result in a dramatic drop in the death rate.
  • It’s not a competition, but rather about saving lives and understanding the relationship between evolution and epidemiology.

20:23 Evolution in inorganic world to cells

  • Recording echoes of organic materials to build evolutionary dynamics
  • Programmatically changing the Earth’s crust through mineral worlds
  • Exploring evolution of oil-water blobs to cells inorganic experiments

23:45 Understanding the mysteries of life and the universe through scientific progress

  • DNA was always a mystery, but now we understand it and can study genetic diseases and the origins of life
  • Exploring the wonder of life and the universe helps us understand and appreciate the awe-inspiring nature of existence

25:35 The theory of signature of life can help determine if something has interacted with a living system or not.

  • The theory was built based on the idea of minimal survival kits and the minimum set of tools needed to create tools.
  • Certain characteristics in the universe, like genetic systems built by evolution, can indicate the presence of life.

29:11 Evolution can be detected through unique characteristics and can be measured in the lab.

  • The artwork created by Professor Lee Cronin is a result of evolution, starting from his ancestors.
  • Professor Cronin’s lab is involved in digitizing chemistry to understand the variables and information needed for evolution.

30:49 Experiments per day are out of reach of manual labor, so a new theory for life was built to produce complexity.

  • The theory of life is based on evolution and the memory in the universe which produces complexity.
  • A measuring device was created to quantify the amount of memory and material needed for the experiment.

34:08 Evolution created biology and biology has sped up the process of evolution.

  • Evolution is not just a vague term of progress in time. It is about the universe storing memories about the past.
  • Chemical systems can remember past events and use that information to react differently in the future.

36:00 The emergence of life on Earth may be as common as the birth of a star in the universe.

  • Some scientists may be conservative about the idea, while others may find it impossible due to religious beliefs.
  • The discovery and understanding of the mechanism of evolution is comparable to the discovery of gravity as a fundamental force.

About this Space

Welcome to Impermanent, my notes on the way to an ontology.

The Genesis of Impermanent: My exploration started as a personal pursuit, driven by an ontological curiosity. As I traversed through various philosophical landscapes, I amassed a wealth of insights. Yet, I faced a recurring challenge – the fleeting nature of this knowledge. Time and again, I struggled to retrieve these pearls of wisdom from the depths of books, notes, videos, websites, and endless online searches.

A Personal Invitation: While Impermanent started as a tool for my own reference,I hope it grows into something more meaningful. Whether you’re a seasoned philosopher, a casual ponderer, or simply someone curious about the deeper questions, you’re welcome here.

Documentary: The Far Future of Consciousness

Transcript Notes:

This video, titled “The Precipice,” presented by the philosopher Toby Ord, explores the concept of humanity’s vulnerability to self-annihilation and its potential cosmic significance.

Our Vulnerability to Annihilation: The video opens with the idea that our current historical moment, which Ord calls “The Precipice,” is defined by humanity’s newfound capacity for self-destruction. This existential risk is a unique feature of the last century, a mere blip in the span of human history.

Cultural Reflection of Impending Apocalypse: The awareness of potential annihilation permeates our culture, art, and media, creating a sense of imminent apocalypse. This includes fears of climate change, nuclear war, and unaligned AI.

Potential for Long-Term Survival: Despite these risks, Ord argues that they are not insurmountable. Humanity still has the potential for long-term survival, with the capacity to explore both the physical universe and the vast realm of consciousness.

Part One – Cosmic Reach: The video then delves into humanity’s potential to settle other planets and traverse the vastness of space, exploring the idea that our descendants could inhabit deep time and significantly impact the cosmic stage.

Earth’s Long-Term Future and Human Interventions: It discusses Earth’s habitability over the next billion years, the gradual changes it will undergo, and how future civilizations might intervene to prolong Earth’s lifespan and habitability.

Moving Beyond Earth: Eventually, the video suggests, humanity will need to move beyond Earth and the solar system to ensure its survival, particularly as the Sun evolves and expands.

Interstellar Travel to Proxima Centauri: The possibility of reaching Proxima Centauri, a nearby star system with an Earth-like planet, is explored. It discusses the challenges and long-term potential of interstellar travel.

Part Two – Life Beyond Earth: The video speculates on the discovery of extraterrestrial life and its implications. It addresses the Fermi Paradox and the potential for advanced life forms that have evolved beyond physical detection.

Part Three – Deep Time: This part discusses the potential for intergalactic travel and the future merger of the Milky Way with Andromeda, leading to a new era of galactic isolation or reunion.

Human Transformation – More Than Human: The video considers how humanity might evolve over millions of generations, embracing enhancements in intelligence, compassion, and other traits, potentially leading to a radical transformation of human experience.

Part Four – The Universal Self: It explores the philosophical concept of Open Individualism, where consciousness is the basis of identity, suggesting that advanced beings in the universe may share common ethical values.

Ethical Convergence and Altruistic Exploration: The idea that advanced civilizations may converge on ethical principles like compassion and cooperation is proposed, potentially driving interstellar exploration as a form of altruistic mission.

The Universal Implications of Consciousness: Finally, the video contemplates the role of conscious life in the universe, suggesting that life and consciousness might be integral to the universe’s fabric and destiny.

Short Summary for Documentary ~ The Far Future of Consciousness in the Universe by Merlin

“The Far Future of Consciousness in the Universe: Cosmic Reach and Humanity’s Potential for Survival”

00:12 Humanity lives in the shadow of existential uncertainty

04:05 Our descendants may be able to block one tenth of the Sun’s incoming light to extend Earth’s habitability.

07:40 Establishing an interstellar civilization would dramatically reduce our vulnerability to natural risks.

11:18 Intelligent life in the universe may have evolved beyond our detection capabilities.

14:52 Our descendants may one day travel to Andromeda or witness the collision of galaxies

18:27 Conscious intelligent life might play an active role in the destiny of the universe.

22:00 Humanity’s transformation through technology is inevitable.

25:37 Consciousness is the carrier of identity and its preservation is crucial for the future

29:14 Future minds may create a biosphere more compassionate than Earth, perceiving reality differently


Detailed Summary for Documentary ~ The Far Future of Consciousness in the Universe by Merlin

“The Far Future of Consciousness in the Universe: Cosmic Reach and Humanity’s Potential for Survival”

00:12 Humanity lives in the shadow of existential uncertainty

  • The risks to our continued existence are real but surmountable
  • The long-term survival of humanity and our descendants is still a possibility

04:05 Our descendants may be able to block one tenth of the Sun’s incoming light to extend Earth’s habitability.

  • By converting the blocked sunlight into usable energy.
  • This feat is far from impossible for an advanced civilization with abundant resources.

07:40 Establishing an interstellar civilization would dramatically reduce our vulnerability to natural risks.

  • Our descendants can plan a voyage to Proxima Centauri with millions of years to spare.
  • We can transport the seeds and cells required to birth new biospheres on new worlds.

11:18 Intelligent life in the universe may have evolved beyond our detection capabilities.

  • The universe has existed for over 14 billion years and has the necessary elements for life to evolve.
  • The lack of visible signals from other civilizations does not necessarily mean they do not exist.

14:52 Our descendants may one day travel to Andromeda or witness the collision of galaxies

  • There are around 50 other galaxies in the vicinity of the Milky Way, including Andromeda
  • Gravity is slowly pulling our galaxy and Andromeda together, and in around 4 billion years the two galaxies will collide

18:27 Conscious intelligent life might play an active role in the destiny of the universe.

  • Enormous galaxies will move towards each other and galactic communities will reunite.
  • Life may reshape the universe, acquire all knowledge, and make the universe conscious.

22:00 Humanity’s transformation through technology is inevitable.

  • Altering human nature may result in losing something of great value.
  • Our descendants will acquire the means to upgrade human traits and explore new forms of culture and cognition.

25:37 Consciousness is the carrier of identity and its preservation is crucial for the future

  • Ethics and morality may converge on universal principles for advanced conscious minds
  • Meeting other conscious beings in the universe can lead to a sense of moral concern and cooperation

29:14 Future minds may create a biosphere more compassionate than Earth, perceiving reality differently

  • Future minds could engineer a biosphere eliminating predation and suffering
  • Perception of reality and the significance of mind may differ in future minds

Australian First People’s Conception of Time / Ontology

Transcript notes:

Spirituality and Oneness: The video begins by highlighting the spiritual beliefs of the First Nations people of Australia, emphasizing a sense of oneness and interconnectedness with all things, living and non-living. It mentions Muduru, a First Nations Australian known for his literary contributions, who spent significant time in India and Nepal, including as a Buddhist monk.

Time and Memory in First Nations Spirituality: The concept of time and memory in First Nations culture is explored. Unlike the Western linear perception of time (past, present, and future), First Nations people perceive time in unique dimensions, deeply intertwined with their spirituality. This is exemplified by the concept of the Dreamtime.

Dreamtime and Creation Stories: Dreamtime is central to First Nations spirituality, explaining the creation of all existence. The video compares this to other creation stories from various cultures, noting that most, including the Big Bang Theory, follow a linear time concept, contrasting with the Dreamtime’s non-linear nature.

Conception of Time in First Nations Culture: First Nations Australians view time as circular and rooted in consciousness, differing significantly from the Western linear concept. This view regards time as states of consciousness rather than a progression through moments.

Ontological States of Consciousness: The video delves into the First Nations’ subtle conception of time, where time is seen as expressions of consciousness, visible or invisible. This perspective posits that nothing ceases to exist; instead, it merely changes in its appearance to consciousness.

Mindfulness and the Present Moment: The video compares the Western spiritual emphasis on being in the ‘now’ with the First Nations’ view. In their understanding, the ‘now’ is a constant state, making the effort to be in the present unnecessary as everything exists perpetually in the now.

Dreamtime Stories and Song Lines: Dreamtime stories, vital to First Nations spirituality, are living narratives explaining the origins and interconnectedness of life and land. These stories, timeless and always relevant, are linked to the landscape through song lines, which are pathways connecting sacred sites and carrying songs, stories, and knowledge.

Memory and Knowledge Preservation: The video compares the First Nations’ methods of preserving knowledge through song lines and Dreamtime stories to the ancient Greeks’ memory palaces. This method involves associating knowledge with the landscape and using memorable narratives.

Environmental Knowledge and Loss: It emphasizes the depth of environmental and natural knowledge possessed by First Nations people, likening their knowledge to a vast, living database. The loss of First Nations cultures is equated to the loss of significant environmental knowledge and understanding.

Reevaluating Time and Existence: Finally, the video invites viewers to consider the First Nations’ conception of time as an alternative to the linear time concept prevalent in Western thought. This view challenges traditional perceptions of existence and creation, offering a unique perspective on stories like The Big Bang Theory.

Short Summary for This 50,000 Year Old Culture Solved The Mystery Of Time by Merlin

“Ancient Australian First Nations Culture: Exploring the Concept of Time and the Dream Time”

00:02 First Nations Australian spirituality is grounded in a sense of oneness and interconnectedness with all of existence.

02:24 The Australian First Peoples have a circular conception of time based on consciousness

04:36 Aboriginal conception of time: Nothing ever ceases to exist, nothing ever changes, everything exists now.

06:58 Australian first people’s conception of time is a more nuanced and sophisticated understanding of time and existence.

09:13 Dreamtime stories exist outside linear time.

11:29 Australian first people’s conception of time is the coincident arising of nothing and something simultaneously

13:46 Ancient Greeks and the first Australians used memory techniques to memorize vast amounts of information.

16:00 Australian First Nations maale held vast amounts of knowledge and were walking, talking, breathing Google search engines.


Detailed Summary for This 50,000 Year Old Culture Solved The Mystery Of Time by Merlin

“Ancient Australian First Nations Culture: Exploring the Concept of Time and the Dream Time”

00:02 First Nations Australian spirituality is grounded in a sense of oneness and interconnectedness with all of existence.

  • The spirituality of First Nations people views time and memory as unique dimensions.
  • The dream time is a central concept in Australian First Nations cultures, explaining the creation of all existence.

02:24 The Australian First Peoples have a circular conception of time based on consciousness

  • Their understanding of time is ontological states of consciousness
  • This conception of time challenges the linear notion of time in creation stories

04:36 Aboriginal conception of time: Nothing ever ceases to exist, nothing ever changes, everything exists now.

  • Objects, events, and people appear to consciousness in either visible or invisible form.
  • Time is an illusion of movement of objects appearing and disappearing to consciousness.

06:58 Australian first people’s conception of time is a more nuanced and sophisticated understanding of time and existence.

  • In their conception of time, the past and future exist but in subtle and invisible forms.
  • There is no ‘now’ in the sense of a present moment sandwiched between past and future. Instead, there are different ways in which existence shows itself.

09:13 Dreamtime stories exist outside linear time.

  • Dreamtime stories coexist in a continuous cycle of creation and existence.
  • Song lines are encoded with ancestral narratives and serve as a multifaceted device for preserving knowledge and cultural wisdom.

11:29 Australian first people’s conception of time is the coincident arising of nothing and something simultaneously

  • The Big Bang Theory is actually a description of now
  • There can be nothing before or after now

13:46 Ancient Greeks and the first Australians used memory techniques to memorize vast amounts of information.

  • The ancient Greeks used the Memory Palace technique to associate details with locations.
  • The first Australians used Dreamtime stories and song lines to remember information.

16:00 Australian First Nations maale held vast amounts of knowledge and were walking, talking, breathing Google search engines.

  • The destruction of natural environments and biodiversity has led to the loss of knowledge and abilities of first peoples.
  • The circular ontological view of time in Australian first people’s conception challenges the linear understanding of time and emphasizes the continuity of the present.


Simple High Level Comparison of Major Schools of Buddhism

AspectTheravadaMahayanaVajrayana
OriginOldest form, based on the Pali Canon.Developed later, based on Mahayana Sutras.Evolved from Mahayana, incorporating Tantric elements.
FocusIndividual enlightenment (Arhatship).Enlightenment for all beings (Bodhisattva ideal).Speedy path to enlightenment using Tantric practices.
Key ConceptsFour Noble Truths, Noble Eightfold Path, Emphasis on monastic life.Emptiness (Sunyata), Compassion (Karuna), Skillful Means (Upaya).Tantra, Mandalas, Rituals, and Guru devotion.
ScripturesPali Canon (Tripitaka).Large body of Mahayana Sutras.Tantras in addition to Mahayana Sutras.
PracticeInsight meditation (Vipassana), adherence to Vinaya (monastic rules).Meditation, Devotional practices, Philosophical study.Visualization, Mantra recitation, Esoteric rituals.
Goal of PracticeAchieving Nirvana and escaping the cycle of rebirth.Achieving Buddhahood for the sake of all beings.Achieving Buddhahood in a single lifetime.
Notable RegionsSri Lanka, Thailand, Burma, Laos, Cambodia.China, Japan, Korea, Vietnam.Tibet, Mongolia, parts of the Himalayas.

Simple High Level Comparison of Major Schools of Vedanta

These are a simple set of tables that I made for quick reference. They catalog different schools of vedanta along with aspects of each school. Of course this is an vast oversimplification of the topic. However, they helped me keep things sorted.

AspectAdvaita VedantaVishishtadvaita VedantaDvaita Vedanta
FounderAdi ShankaracharyaRamanujacharyaMadhvacharya
Basic TenetNon-dualism: Atman (soul) and Brahman (universal soul) are one.Qualified non-dualism: Atman is distinct yet dependent on Brahman.Dualism: Atman and Brahman are eternally separate.
Concept of BrahmanBrahman is the only reality, formless, and beyond attributes.Brahman is with attributes and is the inner controller (Antaryami).Brahman is a personal God, with attributes, separate from the individual soul.
Nature of AtmanIdentical with Brahman, no individuality.Atman is distinct but eternally linked to Brahman.Atman is distinct and different from Brahman.
WorldviewThe world is illusory (Maya) and a manifestation of Brahman.The world is real and a body of Brahman.The world and its entities are real and distinct from Brahman.
Path to LiberationThrough knowledge (Jnana) and realization of the self’s unity with Brahman.Through devotion (Bhakti) and surrender to God.Through a strict dualistic devotion and adherence to Dharma.
Scriptural InterpretationInterpretation of the Upanishads emphasizes non-dualism.Interpretation acknowledges a personal God and individual souls.Stresses a strict dualistic interpretation of the scriptures.
Notable TextsShankaracharya’s commentaries on the Upanishads, Brahmasutra, Bhagavad Gita.Ramanujacharya’s ‘Sri Bhashya’ commentary on the Brahmasutra.Works of Madhvacharya including commentaries on Vedanta texts.
Ethical OutlookEmphasizes renunciation and detachment.Focuses on loving devotion and surrender to God’s grace.Advocates a life of righteousness and strict adherence to duty (Dharma).
AspectAchintya Bheda AbhedaShuddhadvaitaDvaitadvaitaBhedabheda
FounderChaitanya MahaprabhuVallabhacharyaNimbarkacharyaVarious (e.g., Bhaskara)
Basic TenetSimultaneous oneness and difference between the soul and God.Pure non-dualism, Brahman (Krishna) is the only reality with multiplicity.Dualistic non-dualism, a complex relationship between soul and God.Both difference and non-difference between the individual soul and Brahman.
Concept of BrahmanBrahman as Krishna, both distinct and non-distinct from the universe and souls.Krishna as the supreme, singular reality.Brahman is both distinct and non-distinct from the soul and the universe.Brahman is simultaneously different and not different from the universe.
Nature of AtmanSoul is both distinct and non-distinct from Krishna.Soul is a part of Krishna, but maintains individuality.Souls are distinct yet have a non-dual relationship with Brahman.Souls are different yet in some way non-different from Brahman.
WorldviewThe world is a real and dynamic expression of Krishna’s energy.The world is real and a manifestation of Krishna.The world is a real and integral part of Brahman.The world is both real and illusory, with a complex relationship to Brahman.
Path to LiberationThrough devotional service (bhakti) to Krishna.Through loving devotion and the grace of Krishna.Devotion to Radha-Krishna, emphasizing duality and non-duality.Both knowledge and devotion, depending on the specific thinker.
Scriptural InterpretationEmphasizes Bhagavata Purana and Chaitanya’s teachings.Focus on Bhagavad Gita and other scriptures that highlight Krishna’s role.Interpretations emphasize both the unity and duality aspects of scriptures.Varies; some focus on the dual aspects of scripture, others on non-duality.
Ethical OutlookStresses the importance of devotion and community in spiritual life.Focuses on the grace (Pushti) of God and loving devotion.Advocates a balance between devotion and adherence to dharma.Emphasizes a holistic approach combining devotion, knowledge, and ethics.